Highway of Blood is set in West Texas in 1975, it does a great job of capturing the feel of the 1970's. There are several suggestions for 70's metal and rock songs to be played at certain points throughout the adventure, which I thought was quite awesome.
I used Delta Green the Role Playing game to run it. In 1975 Delta Green is in its cowboy era, running illegally with no support, so it fit perfectly with this game. Highway for Blood does provide several interesting plot hooks for different groups of players, and 2 different sets of pre-gens. Also dozens of handouts and NPC portraits, which I printed out on cardstock to pass out to the players like photographs, which was a nice touch.
There is a cool chase scene on the highway, with chase mechanics and vehicle stats. There are Desert hazards such as heat stroke, venomous critters, new spells, creatures and more. There is a lot packed into this adventure, it's more a mini sandbox setting. There is plenty to do and explore, my group played four sessions and did not cover everything, so
I could easily run it for another group and have a completely different
experience.
The physical book is pretty great too. The paper quality, the art, layout, writing, all top notch stuff. You can pick it up on drivethru.